Host Genome x Diet Interaction QTL Database 1.0.
The database is the interface to Jbrowse which enables visualization of host genome (Mus Musculus) QTL and its interaction with diet regulating various physiological and patho-physiogical phenotypes.
The interface also provides SNPs and INDELs from four founder strains i.e. BxD2/TyJ, NZM2410/J, CAST/EiJ and MRL/MpJ for fine-mapping QTL to candidate genes.
AIL Mice QTL Table
The table enumerates genome-wide QTL (p < 0.05) in AIL mice.
| Phenotype | CHR | SNP | Pos | Start | End | LOD | Model |
|---|---|---|---|---|---|---|---|
| IgM (ng/ml) | 12 | UNC21147246 | 54.936 | 54.32637 | 56.67108 | 5.674802 | Diet |
| NAFLDscore | 4 | JAX00568977 | 141.321 | 140.8919 | 142.8408 | 6.295 | Diet |
| Steatosis | 4 | UNC8372857 | 141.414 | 141.0203 | 142.8408 | 7.928 | Diet |
| Eosinophils (%) | X | UNC31178929 | 106.08 | 106.0801 | 106.7164 | 6.209 | Additive |
| Weight 2M (g) | 5 | UNC10261305 | 136.926 | 133.255 | 136.947 | 6.533 | Additive |
| color coat | 2 | UNC4268649 | 154.619 | 153.588 | 154.894 | 28.482 | Additive |
| MCHC (g/dL) | 15 | UNC26237273 | 102.371 | 102.3209 | 102.6428 | 6.91 | Sex |
| HDL (mg/dl) | 12 | JAX00334630 | 56.738 | 56.225 | 57.573 | 5.933 | Sex |
| CRP (pg/ml) | 1 | UNC2210873 | 172.57 | 172.44 | 172.87 | 36.574 | Additive |
| MCHC (g/dL) | 13 | UNC22310805 | 26.913 | 25.499 | 27.136 | 5.846 | Diet |
| Weight 2M (g) | 5 | UNC10031771 | 120.249 | 119.15329 | 122.99564 | 6.046 | Diet |
| Weight 2M (g) | 8 | JAX00166860 | 119.368 | 119.0747 | 121.2548 | 5.719 | Diet |
| Weight 4M (g) | 5 | UNC10031771 | 120.25 | 119.2377 | 120.2563 | 7.32 | Diet |
| Weight 4M (g) | 5 | UNC10420974 | 148.74 | 147.9895 | 148.9458 | 6.87 | Diet |
| Weight 6M (g) | 5 | UNC10031638 | 120.24 | 119.3598 | 122.5474 | 7.39 | Diet |
| MCV (fL) | 13 | JAX00353101 | 26.38 | 25.64851 | 27.04552 | 5.812 | Diet |
| Weight 2M (g) | 6 | UNC11105445 | 53.919 | 53.867157 | 54.534766 | 5.406 | Diet |
| ANA | 17 | UNC27797171 | 33.815 | 33.0898 | 34.88414 | 9.072 | Additive |
| bi Galactose (%) | 12 | UNC120227583 | 113.228 | 113.0044 | 113.4327 | 15.345 | Additive |
| G0 (%) | 4 | UNC7114139 | 40.682 | 40.6447 | 41.74189 | 6.204 | Additive |
| G1 (%) | 4 | UNC7115460 | 40.807 | 40.68183 | 41.74189 | 8.697 | Additive |
| G1S1 (%) | 12 | UNC21923702 | 113.412 | 113.0492 | 113.7299 | 9.494 | Additive |
| G2 (%) | 12 | UNC120227583 | 113.228 | 113.0044 | 113.4327 | 12.198 | Additive |
| G2S1 (%) | 12 | UNC120227583 | 113.2277 | 113.0044 | 113.5741 | 14.916 | Additive |
| G2S2 (%) | 12 | UNC21976746 | 116.498 | 111.4753 | 117.178 | 8.175 | Additive |
| Galactose (%) | 4 | UNC7114139 | 40.682 | 40.6447 | 41.70611 | 6.238 | Additive |
| Mono Galactose (%) | 4 | UNC7115460 | 40.807 | 40.645 | 41.461 | 10.225 | Additive |
| Sialicacid (%) | 12 | UNC21922851 | 113.352 | 113.0492 | 113.5741 | 14.338 | Additive |
| Sialicacid Galactose (%) | 12 | UNC21922851 | 113.352 | 113.1005 | 113.5741 | 16.096 | Additive |
| terminal Galactose (%) | 4 | UNC7119512 | 41.177 | 40.68183 | 41.74189 | 8.43 | Additive |
| MCV (fL) | 15 | UNC26073852 | 89.442 | 88.66051 | 90.80549 | 6.429 | Sex |
| MCV (fL) | X | backupUNC200381363 | 23.945 | 21.55035 | 23.99373 | 6.293 | Sex |
| RDW (%) | 5 | UNC8940486 | 35.198 | 34.8282 | 36.22257 | 5.565 | Sex |
| Lymphocyte (%) | 9 | UNC17122873 | 111.247 | 110.43639 | 112.35564 | 5.829 | Diet |
| Weight 2M (g) | 9 | UNC16800815 | 86.163 | 85.68577 | 86.32703 | 5.621 | Diet |
| HCT (%) | 4 | UNC8200611 | 128.858 | 125.293 | 129.271 | 5.955 | Diet |
| MCV (fL) | 4 | UNC8155357 | 125.684 | 125.5227 | 128.8577 | 7.933 | Diet |
| Weight 4M (g) | 4 | UNC7173132 | 46.195 | 46.0027 | 49.14818 | 5.71 | Diet |
| Weight 4M (g) | 5 | UNC8771430 | 21.614 | 21.05636 | 22.47954 | 5.61 | Diet |
| Weight 6M (g) | 5 | UNC8771430 | 21.614 | 21.45676 | 21.98447 | 8.16 | Diet |
| Weight 6M (g) | 11 | JAX00310397 | 49.115 | 47.00051 | 49.12534 | 5.91 | Diet |
| Weight 6M (g) | 10 | JAX00019795 | 77.016 | 76.696 | 77.06085 | 6.79 | Diet |
| color coat | 7 | UNC13325958 | 88.919 | 83.857 | 92.836 | 29.286 | Additive |
| Weight 6M (g) | 4 | UNC040059085 | 47.699 | 47.38201 | 47.69971 | 7.74 | Diet |
| Weight 6M (g) | 5 | UNC10416935 | 148.5 | 148.4154 | 148.7565 | 5.64 | Diet |
| Ballooning | 9 | UNC16227490 | 41.2 | 41.04046 | 41.2376 | 5.87 | Diet |
| Eosinophils (K/μl) | 3 | UNC5899453 | 105.422 | 105.2927 | 105.532 | 6.299 | Additive |
| Weight 2M (g) | 13 | UNC23461685 | 116.818 | 116.7 | 116.9 | 10.523 | Additive |
| Weight 2M (g) | 9 | UNC16800815 | 86.163 | 86.10062 | 86.32703 | 6.258 | Additive |
| MCHC (g/dL) | X | UNC31319750 | 130.876 | 130.1934 | 131.522 | 6.673 | Sex |
| RDW (%) | 19 | UNC30425204 | 48.284 | 48.22533 | 48.86737 | 6.115 | Sex |
